The International Society of Pharmacoeconomics and Outcomes Research (ISPOR), the Academy of Managed Care Pharmacy (AMCP) and the National Pharmaceutical Council (NPC), have developed questionnaires to help health care decision makers assess and effectively use available comparative effectiveness studies in health technology assessments and/or formulary decisions.

The goal of these questionnaires is to provide greater uniformity and transparency in the use and evaluation of information to improve evidence-based health care decision making for better patient care.

To enhance the functionality and accessibility of these questionnaires, ISPOR has developed an interactive user-friendly version ‘Assessing the Evidence for Health Care Decision Makers’ that includes the following types of studies:

  • Modeling studies
  • Network meta-analysis/indirect treatment comparison studies
  • Prospective observational studies
  • Retrospective observational database studies

‘Assessing the Evidence for Health Care Decision Makers’* provides users with:

1) Interactive questionnaires to help determine if the study is: a) relevant to the setting/decision in question and b) credible enough to include in the overall body of evidence.
2) A personalized web-based database to: a) store their assessments and b) access them anywhere at any time.

General structure of the questionnaire
Each questionnaire includes two main sections: a) relevance and b) credibility. Credibility is further divided into several domains. Upon completing the questionnaire the user will be able to make a more substantiated judgment regarding the relevance and credibility of a study to inform a decision. No summary score is provided for the overall questionnaire or for the domains of the credibility section. This was an explicit choice in the design of these questionnaires, since individuals may place greater or lesser weight on the response to any individual question. However, some 'credibility' questions are considered critical; a negative answer to these questions suggests the presence of a “fatal flaw”. It is up to each user to decide how these answers affect the overall credibility of the study.

*In order to obtain the full potential of the assessment you are encouraged to answer as many questions as possible.

Modeling studies

Network meta-analysis/Indirect Treatment Comparison

Observational Study